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Complete biosynthesis of nicotine

This Cell paper completes the nicotine biosynthesis pathway by identifying the final coupling reaction, a 5-component metabolon, and a MATE transporter required for efficient nicotine production and transport.

Classified for Enzo Simier.

Why it was queued

It clarifies a major plant alkaloid pathway and offers useful ideas for engineering pest resistance in crops.

Classifier notes

Source: https://www.cell.com/cell/fulltext/S0092-8674(26)00335-1